A serious multi-vehicle crash has closed both ways of the A36 between Limpley Stoke and Farleigh Hungerford.
Police were alerted to the scene at around 7.30pm, with members of the public stopping to help the injured drivers.
The crash happened at the junction of the B3110 Branch Road near Hinton Charterhouse onto the A36 towards Limpley Stoke.
The road is expected to re-open at around 10.30pm.
This story has been updated with more information, you can find it here.